Genetic variation in selenoprotein genes, lifestyle, and risk of colon and rectal cancer.
Associations between selenium and cancer have directed attention to role of selenoproteins in the carcinogenic process.We used data from two population-based case-control studies of colon (n = 1555 cases, 1956 controls) and rectal Suits (n = 754 cases, 959 controls) cancer.We evaluated the association between genetic variation in TXNRD1, TXNRD2, TX